100013-Acetone Empure Merck

100013-Acetone Empure Merck

**Description**
Catalogue Number	100013
Synonyms	Dimethyl ketone, Propanone, 2-Propanone

**Toxicological Information**
LD 50 Oral	LD50 Rat 5800 mg/kg
LD 50 dermal	LD50 Rabbit 20000 mg/kg

**Safety Information according to GHS**
Hazard Pictogram(s)
Hazard Statement(s)	H225: Highly flammable liquid and vapour. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness. EUH066: Repeated exposure may cause skin dryness or cracking.
Precautionary Statement(s)	P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P240: Ground/bond container and receiving equipment. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal Word	Danger
RTECS	AL3150000
Storage class	3 Flammable liquids
WGK	WGK 1 slightly water endangering
Disposal	1 Strongly contaminated halogen-free organic solvents: container A.

**Safety Information**
Hazard Symbols
Categories of danger	highly flammable, irritant
R Phrase	R 11-36-66-67 Highly flammable.Irritating to eyes.Repeated exposure may cause skin dryness or cracking.Vapours may cause drowsiness and dizziness.
S Phrase	S 9-16-26-46 Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.If swallowed, seek medical advice immediately and show this container or label.

**Specifications**
Assay (GC)	≥ 99.0 %
Identity (IR)	conforms
Identity B (Ph Eur)	conforms
Identity C (Ph Eur)	conforms
Identity B (NF)	conforms
Identity (JPE)	conforms
Water-insoluble substances	conforms
Appearance of solution	conforms
Acidity or alkalinity	conforms
Density (d 20 °C/20 °C)	0.790 - 0.793
Density (d 25 °C/25 °C)	≤ 0.789
Reducing substances	conforms
Readily oxidizable substances	conforms
Potassium permanganate-reducing substances	conforms
Phenole	conforms
Related substances (GC) (Methanol (Impurity A))	≤ 0.05 %
Related substances (GC) (2-Propanol (Impurity B))	≤ 0.05 %
Related substances (GC) (Benzene (Impurity C))	≤ 2 ppm
Related substances (GC) (other impurity)	≤ 0.05 %
Cyclohexane (residual solvent) (GC)	≤ 0.01 %
Other residual solvents (ICH Q3C)	excluded by the manufacturing process
Evaporation residue	≤ 0.0020 %
Water	≤ 0.30 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*). Conforms to Ph Eur, BP, JPE, NF